Last updated: February 1, 2026
The 2025 ACC/AHA guidelines define four core pillars for comprehensive heart failure management: guideline-directed medical therapy (GDMT), device therapy optimization, remote patient monitoring, and lifestyle modification with comorbidity management.
Modern software platforms reinforce these pillars through integrated workflows. GDMT compliance tracking confirms that patients receive appropriate pharmacological therapy. Device therapy modules monitor CIED performance, battery status, and therapeutic delivery. RPM capabilities track daily weights, blood pressure, and thoracic impedance. Lifestyle tools support medication adherence, reminders, and patient education.
Rhythm360 supports all four pillars through a multi-modality platform that combines CIED monitoring with HF and HTN RPM services, AI-powered alert triage, and automated billing compliance for coordinated heart failure care.
Rhythm360 serves as a vendor-neutral platform for heart failure management and delivers more than 99.9% data reliability through redundant feeds and AI-powered normalization. The platform unifies data from all major device manufacturers and provides comprehensive RPM services for heart failure and hypertension patients.
Key features include bi-directional EHR integration with Epic, Cerner, Athenahealth, eClinicalWorks, Greenway Health, and other systems. Clinicians gain secure mobile app access while on call. Automated CPT code capture supports billing for 99453, 99454, and 99457. The AI-driven alert system reduces response times by 80% through intelligent triage. A SaaS-based pricing model scales with clinic size and platform usage.
Pros: Complete vendor neutrality, up to 300% revenue growth, weekend and holiday alert coverage, HIPAA-compliant mobile access
Cons: Requires initial staff training, premium pricing for advanced AI features
Schedule a demo to see 80% faster alerts in action.
Murj focuses on AI-driven analytics for early detection of worsening heart failure via non-invasive sensors. The platform emphasizes daily weight monitoring, blood pressure tracking, and medication adherence through patient-friendly interfaces.
Murj reports 30% to 40% reductions in hospital readmissions and provides HIPAA-compliant clinician dashboards. The platform primarily targets CIED remote monitoring across vendors and shows some limitations for non-partnered devices. Higher subscription costs may challenge smaller practices.
Pros: Strong patient engagement, documented readmission reduction, intuitive interface
Cons: Some device vendor limitations, higher costs for small practices
PaceMate delivers unified monitoring for CIED and heart failure patients with AI-powered risk stratification and predictive alerts. The platform excels at real-time data integration from ICD and CRT-D devices and incorporates HF-specific biomarkers such as thoracic impedance.
PaceMate reports 25% improvements in patient adherence and revenue capture through billing automation. The platform maintains strong interoperability with major device manufacturers, including Medtronic and Abbott. It relies heavily on implanted devices and occasionally experiences EHR integration delays.
Pros: Strong device manufacturer relationships, proven adherence improvements, automated billing
Cons: Heavy CIED dependency, limited non-device RPM, occasional EHR integration delays
Implicity’s cloud-based platform supports remote monitoring of cardiac devices and uses advanced AI algorithms for arrhythmia detection linked to HF decompensation. The vendor-agnostic system supports multiple CIED brands and offers customizable alerts and population health analytics.
The platform achieves 50% faster alert triage and holds strong EU MDR certification that extends to US markets. Implicity presents a steeper learning curve for non-specialists and carries premium pricing. Native support for wearable-only HF monitoring remains limited.
Pros: Vendor-agnostic support, scalable for large clinics, strong regulatory compliance
Cons: Complex interface, premium pricing, limited wearable support
Octagos Health focuses on AI-enhanced RPM for electrophysiology and HF with emphasis on operational efficiency and financial performance. The platform offers unified dashboards for CIED and HF vitals, automated prior authorization for remote monitoring billing, and predictive analytics for readmission risk.
Octagos integrates with more than 20 EHR systems and supports up to 200% RPM revenue growth through claim scrubbing. Typical deployment completes in under 30 days. As a newer 2026 entrant, the platform has a smaller user base and less mature AI compared with established competitors.
Pros: Cost-effective pricing, broad EHR compatibility, quick deployment
Cons: Newer platform, smaller user base, less mature AI algorithms
Rhythm Management Group combines monitoring services with software, which creates a hybrid approach to heart failure management. The company provides dedicated monitoring staff alongside technology solutions and appeals to practices that want outsourced monitoring support.
The service model reduces internal staffing requirements but may limit practice flexibility and customization compared with pure software platforms such as Rhythm360.
Pros: Dedicated monitoring staff, reduced internal burden
Cons: Less practice control, potential service dependencies
Merge Cardio represents a legacy database system that focuses on secure data management and centralized imaging. KLAS ratings highlight its role for established practices. These on-premise solutions lack modern cloud functionality, AI capabilities, and workflow automation that 2026 heart failure programs now expect.
Pros: Established user base, strong security record
Cons: Limited cloud functionality, no modern AI features, minimal workflow automation
Feature | Rhythm360 | Murj/PaceMate | Implicity/Octagos |
Vendor-Neutral | Complete | Limited | Partial |
AI Alert Reduction | 80% | 40-60% | 50-60% |
Mobile App | Full HIPAA | Basic | Limited |
Revenue Growth | 300% | 200% | 150-200% |
The new CPT codes 99445 and 99470, effective January 1, 2026, expand RPM access for heart failure patients. CPT 99445 covers monitoring vital signs with at least 2 days of data transmission and fits stable heart failure patients who track their weight 2 to 3 times per week. Rhythm360’s automated billing system maintains compliant documentation for these codes along with 99453, 99454, and 99457.
AI-enhanced ECG and PPG algorithms detect heart failure decompensation early and improve alert triage in cardiac RPM. Modern platforms cut alert volume by 40% to 80% through machine learning models that separate clinically significant events from routine transmissions.
Small practices gain significant value from vendor-neutral platforms that remove the burden of juggling multiple OEM portals. Rhythm360’s unified interface allows teams to monitor patients with devices from any manufacturer in one place. This approach reduces training requirements and day-to-day operational complexity.
Transform your heart failure management approach and simplify device workflows. Schedule a demo to see how Rhythm360 delivers vendor-neutral performance.
The four pillars of heart failure management include guideline-directed medical therapy, device therapy optimization, remote patient monitoring, and lifestyle modification with comorbidity management. These pillars work together to deliver comprehensive care that addresses medications, device-based therapies, continuous monitoring, and patient education. This structure improves outcomes and reduces hospitalizations.
Effective cardiology practice management software combines comprehensive CIED monitoring, RPM capabilities, EHR integration, and automated billing. Rhythm360 leads this category with a vendor-neutral platform that unifies data from all device manufacturers, provides AI-powered alert triage, and automates CPT code capture to support higher and more accurate revenue.
Rhythm360 offers complete vendor neutrality, 80% alert reduction, and 300% revenue growth potential. Murj centers on sensor-based HF monitoring with strong patient engagement but limited device vendor support. PaceMate excels in CIED and HF integration with strong manufacturer relationships and relies heavily on implanted devices. Rhythm360 delivers the broadest coverage across heart failure management scenarios.
New 2026 CPT codes include 99445 for short-term vital sign monitoring that requires at least 2 days of data transmission in a 30-day period. Code 99470 covers brief RPM management for the first 10 minutes plus one live interaction. These codes complement 99453, 99454, and 99457 and expand billing opportunities for heart failure remote monitoring services.
AI improves heart failure alert triage by analyzing patterns in physiological data and separating routine variation from clinically significant change. Machine learning models reduce false alarms and continuously learn from patient-specific data to support personalized monitoring. These systems detect subtle changes before symptoms appear and prioritize alerts by clinical urgency, which often results in 40% to 80% reductions in alert volume.
Modern, integrated platforms such as Rhythm360 replace fragmented legacy systems and reshape heart failure management. Competitors offer strong niche capabilities, while Rhythm360’s vendor-neutral design addresses the full spectrum of cardiology practice needs, from unified device monitoring to automated billing compliance.
Rhythm360’s record of 80% alert reduction and 300% revenue growth, combined with onboarding that often completes within days to weeks, positions practices for rapid operational improvement and long-term success in value-based care models.
Unify CIED and HF monitoring and grow revenue. Schedule a demo today.
