5 Best Enterprise Arrhythmia Monitoring Software Options

Last updated: January 27, 2026

Key Takeaways for Cardiology Leaders

  1. Enterprise arrhythmia monitoring software cuts response times by 80%, reduces alert fatigue by 70%, and increases revenue using 2026 Medicare RPM codes like CPT 99445, 99470, and 93298.
  2. Rhythm360 leads as the #1 vendor-neutral AI platform, unifying data from all OEM devices with more than 99.9% reliability and bi-directional Epic and Cerner integration.
  3. Competitors such as PaceMate, Murj, Implicity, and legacy Paceart cover parts of the workflow but lack full multi-OEM unification, advanced AI triage, and complete RPM support.
  4. AI-powered alert filtering with certified technician oversight prevents missed arrhythmias, which reach 64% undetected in the first 48 hours, while improving billing accuracy for higher reimbursement.
  5. RhythmScience and Rhythm360 support enterprise-scale transformation, unifying data silos and enabling up to 300% revenue growth. Schedule a demo today.

1. Rhythm360 (RhythmScience): Vendor-Neutral AI Platform for Enterprise Cardiology

Rhythm360 serves as a vendor-neutral platform that unifies data from all major OEM devices, including Medtronic, Abbott, Boston Scientific, and Biotronik, through API, HL7, XML, and OCR connections. Its AI-powered triage system delivers more than 99.9% data transmissibility, which helps prevent missed ventricular tachycardia events and cuts critical alert response times by 80%. Bi-directional Epic and Cerner integration keeps workflows inside the EHR, while a secure Twilio-powered mobile app supports 24/7 patient oversight.

Rhythm360 supports heart failure and hypertension RPM, automated CPT capture for 93298, 93299, 99454, and related codes, plus optional certified cardiac technician review. Practices report up to 300% revenue growth through accurate billing and streamlined operations. One real-world example includes Saturday morning atrial fibrillation detection with same-day anticoagulation, which prevented a likely stroke.

The SaaS pricing model scales with practice size and automatically captures Medicare RPM codes to maintain compliance. Rhythm360 covers the full enterprise arrhythmia monitoring lifecycle, from data ingestion and triage to documentation and billing.

Rhythm360
Rhythm360

2. PaceMate: Cloud Successor to Legacy Paceart

PaceMate functions as a cloud-based successor to Paceart after its acquisition from Medtronic and supports CIEDs, implantables, wearables, and ambulatory monitors. It improves accessibility compared with legacy on-premise systems and offers cloud storage with workflow automation for cardiac device management, which appeals to practices moving away from traditional Paceart deployments.

Key strengths include familiar layouts for former Paceart users, cloud access for remote monitoring, and proprietary Auto-Triage for alert prioritization. Limitations appear in vendor-neutral depth, with stronger Medtronic integration than other OEMs. The platform also may not match the level of 24/7 certified technician oversight available with Rhythm360, which can increase the risk of delayed responses for high-risk events.

PaceMate suits practices that want a cloud upgrade from Paceart but do not require full multi-OEM unification or advanced AI workflows for large enterprise environments.

3. Murj: Focused Workflow Automation for Device Clinics

Murj positions itself as a cloud platform centered on workflow automation for cardiac device monitoring and targets practices that want simpler administrative processes. It offers core cloud infrastructure and automated reporting for routine device follow-ups.

These automation tools reduce manual work and can help smaller practices with straightforward monitoring needs. However, Murj provides limited multi-OEM unification and basic alert management compared with more comprehensive platforms.

Relative to Rhythm360, Murj does not match the depth of vendor-neutral data integration, AI-powered alert triage, Twilio-based communication, or full heart failure and hypertension RPM capabilities that large cardiology groups often require.

4. Implicity: AI-Driven Alert Filtering for Arrhythmia Monitoring

Implicity concentrates on AI-powered alert filtering for cardiac device monitoring and targets the problem of alert fatigue in busy cardiology practices. Its algorithms reduce non-actionable notifications and highlight clinically meaningful events.

This AI focus can lower false-positive alerts and ease clinician burnout while maintaining arrhythmia detection. The platform performs well in algorithmic detection and basic prioritization.

Implicity’s narrow scope limits its data ingestion and vendor-neutral unification compared with Rhythm360. It does not provide the same level of mobile oversight, integrated communication, or end-to-end enterprise monitoring workflows.

5. Paceart (Legacy On-Prem): Stable but Limited for Modern Workflows

Legacy Paceart operates as an on-premise database primarily built for Medtronic device management and still underpins many long-standing cardiology workflows. It offers basic tools for storing and retrieving cardiac device data.

These systems remain stable for practices that prefer on-premise infrastructure and Medtronic-focused workflows. Their long use history shows reliability for fundamental device data management.

However, on-premise architecture creates data silos, restricts cloud access, and lacks AI triage and mobile oversight. Many practices now plan cloud migration to vendor-neutral platforms such as Rhythm360 for multi-OEM integration and modern automation.

Enterprise Arrhythmia Monitoring Software Comparison Table

Platform

Cloud/Vendor-Neutral

AI Alert Reliability

EHR Integrations

Scalability/ROI

Rhythm360

Yes/Yes

>99.9%, 80% faster

Epic/Cerner/HL7 FHIR

Enterprise, 300% revenue

PaceMate

Yes/Partial

Moderate

Extensive (700+)

Good

Murj

Yes/No

Basic

Partial

Mid

Implicity

Yes/No

Strong AI

Basic

Mid

Reducing Alert Fatigue in Cardiology Device Clinics

Alert fatigue strains modern cardiology teams, and UCSF Health cut alerts by 70% through systematic threshold changes. Effective reduction requires an AI triage that removes non-actionable notifications while preserving the detection of dangerous events.

Rhythm360 combines intelligent filtering algorithms with certified technician oversight so clinicians see only clinically significant alerts. The system learns each patient’s baseline and triggers alerts for meaningful deviations, which restores urgency and improves actionability. AI-integrated RPM workflows reduce false positives and shorten intervention times.

Successful implementation includes setting thresholds based on protocols, defining escalation paths for each alert type, and using real-time feedback to refine filters. Practices typically see sharp drops in alert volume while maintaining or improving patient safety.

2026 Medicare Reimbursement Strategy for Remote Cardiac Monitoring

CMS added CPT codes 99445 and 99470 in the 2026 physician fee schedule to close RPM reimbursement gaps. CPT 99445 supports patients with 6 to 15 days of data at about $47 nationally, which removes barriers for intermittent monitoring. CPT 99470 reimburses micro-interventions for 10 to 19 minutes of monitoring at about $26.

Core codes still matter, including CPT 93298 and 93299 for CIED monitoring, CPT 99454 for device supply with 16 or more days of data, and CPT 99457 and 99458 for clinical time. Foundational RPM codes continue with 99457 at about $52 for the first 20 minutes and 99458 at about $41 for each additional 20 minutes.

Rhythm360 automatically captures and documents all eligible CPT codes, which supports Medicare compliance and maximizes revenue. Automated billing support reduces manual errors and ensures consistent code use across monitoring programs. Schedule a demo to explore Medicare reimbursement optimization.

Bi-Directional EHR Integration for Cardiac Device Workflows

Modern cardiac monitoring platforms require tight EHR integration using HL7 FHIR R4 and SMART on FHIR 2.1 for Epic and Cerner. Epic relies on SMART on FHIR with OAuth2, and Cerner supports FHIR DSTU2 and R4. TEFCA’s QHIN framework and CMS rules now expect transparent FHIR endpoints.

Rhythm360 delivers bi-directional integration with Epic, Cerner, and Athenahealth through full HL7 FHIR support. Robust data mapping, transformation, and HIPAA-compliant security maintain stability and protect workflows. Cardiac device data, alerts, and billing documentation flow directly into the EHR.

This integration removes manual data entry, cuts transcription errors, automates documentation, and supports coordinated care across providers. Bi-directional data flow keeps EHR updates synchronized with the monitoring platform while device data populates the correct EHR fields in real time.

Paceart Cloud Migration Paths with Rhythm360

Practices running legacy Paceart now face pressure to move to cloud platforms that support vendor-neutral data and modern automation. Successful migration requires planning for data continuity and staff adoption.

Key steps include assessing current Paceart data and export options, evaluating cloud platforms for multi-OEM support, planning staff training and workflow changes, running parallel systems during transition, and then completing data migration and cutover.

Rhythm360 stands out as a leading Paceart alternative with full cloud infrastructure, vendor-neutral unification, AI workflows, and deep EHR integration. Its migration services include data transfer assistance, structured training, and technical support for a smooth shift from legacy systems.

Frequently Asked Questions About Enterprise Arrhythmia Monitoring

What is the cost of Zio compared with enterprise platforms?

Zio patch monitoring usually costs $300 to $500 per patient episode for 14-day monitoring. Enterprise platforms such as Rhythm360 use SaaS subscriptions that scale with practice size and patient volume. These platforms support ongoing monitoring across multiple device types and chronic conditions, which often delivers better long-term value for large populations with CIEDs and chronic cardiovascular disease.

Does Medicare cover CIED monitoring in 2026?

Medicare covers CIED monitoring through several CPT codes. Codes 93298 and 93299 support initial setup and ongoing monitoring, while 99454 supports remote physiological monitoring. Proper documentation and billing allow practices to receive full reimbursement for remote cardiac monitoring services.

How does Rhythm360 reduce alert fatigue?

Rhythm360 reduces alert fatigue with AI triage that filters non-actionable notifications and highlights clinically important events. The platform learns each patient’s baseline and triggers alerts for meaningful changes. Optional certified technician oversight adds another review layer and clinical context for complex cases.

What are the key differences between Rhythm360 and PaceMate?

Rhythm360 offers full vendor-neutral integration across all OEM devices, AI-driven alert triage, bi-directional EHR integration, mobile oversight, and integrated heart failure and hypertension RPM. PaceMate supports many cardiac devices in a cloud platform with Auto-Triage and broad EHR integrations, with particularly strong Medtronic support, but only partial vendor-neutral capabilities compared with Rhythm360’s enterprise feature set.

What devices support remote monitoring for arrhythmias?

Remote monitoring devices for arrhythmias include implantable pacemakers, ICDs, and loop recorders, along with wearables such as Holter monitors, event recorders, and patch monitors. These devices continuously or intermittently track heart rhythm and transmit data to care teams for review and intervention. Modern platforms bring data from all these device types into a single monitoring workflow.

Conclusion: Rhythm360 as the Enterprise Arrhythmia Monitoring Hub

Rhythm360 addresses core challenges for cardiology practices in 2026, including OEM data silos, missed critical events, alert fatigue, and billing gaps. Its vendor-neutral design, AI workflows, deep EHR integration, and automated billing support deliver faster response times and documented revenue gains up to 300%.

The current cardiac monitoring landscape favors platforms that unify data and provide intelligent clinical decision support. Rhythm360 covers the full enterprise arrhythmia monitoring journey, from ingestion and triage through documentation and reimbursement. Schedule a demo to see how Rhythm360 can streamline operations and unlock significant revenue growth through modern cardiac monitoring workflows.

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