Last updated: July 13, 2026
A modern EP workflow automation platform ingests and normalizes data from all major CIED manufacturers, including Medtronic, Abbott, Boston Scientific, and Biotronik, through a single vendor-neutral interface. The platform applies AI-powered alert triage to filter non-actionable transmissions and surface clinically significant events in priority order. It delivers bi-directional integration with Epic, Cerner, and other major EHR systems using HL7 FHIR R4 standards mandated by CMS. It also automates the documentation required to support compliant billing for CPT codes 93298, 93299, and related remote monitoring codes, without adding manual steps for clinical or administrative staff.
The following table summarizes how Rhythm360 addresses these requirements across seven core capability areas.
| Capability | Rhythm360 |
|---|---|
| Multi-OEM Support | Medtronic, Abbott, Boston Scientific, Biotronik, and others via API, HL7, XML, and computer vision PDF parsing |
| AI Alert Triage | AI-powered prioritization of clinically significant events, filters non-actionable transmissions, optional 24/7/365 CCT oversight |
| Data Transmissibility | >99.9% via redundant data feeds, computer vision, and AI-powered extrapolation |
| Bi-Directional EHR Integration | Epic, Cerner, Athenahealth, eClinicalWorks, Greenway Health, and others via HL7/FHIR |
| Automated CPT Billing Documentation | Automated documentation for CPT 93298, 93299, 99454, 99457, 99458, and related codes |
| Mobile Access | Secure, HIPAA-compliant mobile app for transmission review, report signing, and care coordination |
| HF/HTN RPM Service-Line Expansion | Integrated Rhythm-CIED and HF/HTN RPM service lines with patient onboarding and automated billing support |
| Implementation Timeline | Days to weeks, including EHR integration setup |
The HRS White Paper on CIED data interoperability identifies the core technical problem: each manufacturer has developed proprietary nomenclature, technical standards, and communication protocols, and traditional EHR systems are not well suited to managing the resulting data. As soon as a practice implants devices from more than one OEM, staff must log into multiple non-interoperable portals to retrieve patient data, which creates data silos and unsustainable administrative burden.
Surveys of device clinic staff identify managing disconnected patients, initial transmission review, and patient phone calls as among the most burdensome tasks that staff are most willing to outsource. Many clinics rate their staffing as insufficient for remote monitoring workloads.
Rhythm360 resolves the multi-portal problem through a vendor-neutral architecture that ingests data from Medtronic, Abbott, Boston Scientific, Biotronik, and other manufacturers using API connections, HL7 feeds, XML parsing, and computer vision-based PDF extraction. All data is normalized into a single dashboard, which eliminates redundant logins and manual transcription. The platform’s redundant data feed system acts as a fail-safe when an OEM server is unavailable and maintains greater than 99.9% transmissibility across the patient population. University of Chicago Medicine processed more than 73,000 reports annually through Rhythm360 in 2025, averaging more than 18,000 reports per quarter, which demonstrates the platform’s capacity for high-volume, multi-manufacturer environments.
Remote monitoring billing for CIEDs depends on precise documentation of transmission events within defined lookback windows. CPT 93298 covers remote interrogation of implantable loop recorders and subcutaneous cardiac rhythm monitors for periods up to 30 days, and billing outside the specified window triggers CO-18 duplicate denials. Manual workflows make it structurally difficult to track these windows across a large patient panel.
A cardiology practice with 500 remotely monitored patients using a manual workflow typically bills CPT 99457 on only 60–70% of eligible patient-months and CPT 99454 on 75–85%. This gap represents lost revenue that automation can recover. Automated workflows push CPT 99457 capture above 90% and eliminate CPT 99454 denials for missed transmission thresholds. A 500-patient cardiology RPM program typically sees $300,000 to $500,000 per year in incremental captured revenue from automation. Additionally, automating tracking of the 90-day billing window for CPT codes helps maximize revenue from CIED monitoring programs.
Rhythm360 automates the documentation required for CPT 93298, 93299, 99454, 99457, 99458, and related codes. The platform tracks billable events against the applicable lookback windows, generates compliant documentation, and surfaces captured and potential revenue in the administrative dashboard. University of Chicago Medicine reported improved billing and accountability for patients following Rhythm360 integration. Practices implementing Rhythm360 have reported revenue increases of up to 300% through improved CPT code capture and better staff efficiency.
Seamless HL7 FHIR flows between RPM platforms and EHRs remain a challenge for many U.S. hospitals, and IT leaders often cite data exchange as a top barrier to RPM adoption. Manual EHR entry of CIED transmission data is time-consuming, error-prone, and creates documentation gaps that affect both clinical decision-making and billing compliance.
CMS interoperability policies require HL7 FHIR Release 4.0.1 as the core standard for exchanging clinical and administrative health data, and the CMS Interoperability and Prior Authorization Final Rule phases in FHIR API mandates effective January 2027. Platforms that do not support bi-directional HL7 FHIR flows will face increasing compliance and operational pressure.
Rhythm360 delivers bi-directional EHR integration with Epic, Cerner, Athenahealth, eClinicalWorks, Greenway Health, and others via HL7 and FHIR. Data flows in both directions. Device transmissions, alerts, and reports write directly into EHR encounters and progress notes. Patient demographics, diagnoses, and medications are pulled from the EHR into the Rhythm360 dashboard. Implementation, including EHR integration setup, takes days to weeks rather than months.
Next-generation remote monitoring replaces static thresholds with AI-driven trajectory analysis and intelligent alert triage to prioritize events most likely to benefit from intervention. Without structured workflows, AI alerts may fail to translate into clinical utility despite their predictive accuracy, which underscores the need for EHR integration, clinician trust, and defined accountability mechanisms.
In a nonrandomized study presented at THT 2026, an AI-enabled virtual HF care platform generated 2,013 red alerts over a median 124-day enrollment period, with 99.26% reviewed within 48 hours and 81% resolved at the first triage step. This result demonstrates that structured AI triage workflows can handle high alert volumes without increasing cardiologist workload.
Rhythm360’s AI-powered alert triage system filters non-actionable transmissions and surfaces clinically significant events such as new-onset atrial fibrillation, ventricular tachycardia, lead malfunction, and ERI or RRT indicators in priority order. The platform also offers optional 24/7/365 oversight by certified cardiac technicians supervised by physicians, which provides a human layer of review for the highest-acuity events. As noted by Andrew Beaser, MD at University of Chicago Medicine, Rhythm360 enabled clinicians to review more transmissions daily and identify more abnormalities. Practices using Rhythm360 report an 80% reduction in critical alert response times.
As described earlier, Rhythm360’s vendor-neutral architecture ingests data from all four major manufacturers into a single unified dashboard, which eliminates the multi-portal workflow that creates data silos. The platform also supports CardioMEMS pulmonary artery monitors and other specialized sensors. The HRS White Paper on CIED interoperability identifies the need for a single IT system capable of managing multi-manufacturer patient data, and Rhythm360’s architecture fulfills that requirement.
Clinics automate CPT 93298 and 93299 documentation by using a platform that tracks transmission events against the applicable 30-day lookback windows, generates compliant clinical documentation from ingested device data, and surfaces billing-ready records without manual entry. Rhythm360 performs this function automatically. As transmissions are received and processed, the platform generates the documentation required for compliant billing, tracks window eligibility across the patient panel, and flags missed opportunities before the billing period closes. A correctly stacked CCM and RPM workflow captures $1,300 or more per complex cardiac patient per year across applicable CPT codes.
Rhythm360 provides bi-directional Epic integration for CIED data using HL7 and FHIR protocols. Device transmission data, alerts, and clinical reports flow from Rhythm360 into Epic encounters and progress notes. Patient demographics, active diagnoses, and medication records flow from Epic into the Rhythm360 dashboard. This integration eliminates manual EHR entry for clinical staff and keeps the EHR record aligned with the most current device data. HL7 FHIR R4 remains the production standard for RESTful health data exchange, and Rhythm360’s integration layer is built on this standard. Implementation of the Epic integration fits within the platform’s standard onboarding timeline of days to weeks.
Clinic administrators and electrophysiologists can use the following questions to evaluate EP workflow automation platforms against their requirements.
Rhythm360 addresses each of these questions directly. Schedule a demo to walk through Rhythm360’s capabilities against your clinic’s specific workflow requirements.
Rhythm360’s SaaS-based pricing model scales with clinic size and platform usage, which makes it accessible for independent EP clinics and large integrated health systems.
The financial case for automating EP clinic workflows is measurable and documented. Practices implementing Rhythm360 have reported an 80% reduction in critical alert response times and revenue increases of up to 300% through improved CPT code capture, better staff efficiency, and the addition of HF and HTN RPM service lines. Recovering even 75% of lost CPT 99454 revenue on a 500-patient panel yields approximately $50,000–$70,000 per year, and automating the tracking of billing windows for CPT codes can generate additional revenue for CIED monitoring programs. These figures do not include the operational savings from eliminating manual data retrieval, redundant EHR entry, and staff time spent navigating OEM portals.
Rhythm360 is a vendor-neutral platform that ingests data from Medtronic, Abbott, Boston Scientific, Biotronik, and other manufacturers through a single unified interface. The platform uses API connections, HL7 feeds, XML parsing, and computer vision-based PDF extraction to normalize data from each manufacturer into a consistent format. Clinical staff access all device data through one dashboard without logging into separate OEM portals. The platform also supports CardioMEMS pulmonary artery monitors and other specialized sensors and includes integrated service lines for HF and HTN remote physiological monitoring.
Rhythm360 maintains greater than 99.9% transmissibility through a combination of redundant data feeds, computer vision-based extraction, and AI-powered data extrapolation. When a primary OEM data feed is unavailable because of server downtime or connectivity issues, the redundant feed system activates automatically to retrieve the transmission. For data arriving in unstructured PDF formats, computer vision and optical character recognition extract and normalize the relevant fields. AI-powered extrapolation fills gaps where data points are incomplete and gives clinicians a complete and accurate view of each patient’s device status.
Rhythm360 automates documentation for CPT 93298, 93299, 99454, 99457, 99458, and related remote monitoring codes. The platform tracks each patient’s transmission history against the applicable lookback windows, which include 30 days for implantable loop recorder and subcutaneous cardiac rhythm monitor codes and 90 days for pacemaker and ICD interrogation codes. It generates compliant billing documentation as transmissions are processed. The administrative dashboard surfaces captured revenue and flags patients approaching or past their billing window eligibility, which allows staff to act before the opportunity closes. This automated tracking eliminates the manual reconciliation that causes missed claims and CO-18 duplicate denials in manual workflows.
Rhythm360 includes a secure, HIPAA-compliant mobile application that allows electrophysiologists, cardiologists, nurse practitioners, and other clinical staff to review transmissions, sign reports, and coordinate care from their smartphones. The mobile app provides access to the same prioritized alert queue and patient data available on the desktop platform. Clinicians can respond to critical events, such as new-onset atrial fibrillation or ventricular tachycardia flagged on a weekend, without being physically present in the clinic. All mobile access is audit-logged and encrypted in compliance with HIPAA Security Rule requirements.
The standard Rhythm360 implementation timeline, including EHR integration setup with Epic, Cerner, Athenahealth, eClinicalWorks, Greenway Health, or other supported systems, is days to weeks. The platform’s SaaS-based architecture avoids the extended deployment timelines associated with on-premise systems. RhythmScience supports customers through EHR marketplace approvals and integration configuration, and the onboarding process includes patient population setup, OEM data feed connections, and staff training. Practices can begin reviewing transmissions through the unified dashboard shortly after go-live.
Schedule a demo to see Rhythm360’s full capabilities and discuss implementation for your clinic.
